Regional brain age gap

1. Regional brain age gap impairs physical function in humans.

   “A higher brain age gap in these regions was associated with declines in cognitive, motor, and functional performance.”

   Humansin persons with Huntington's diseasesubcortical, temporal, and parietal brain regions

   Mapping Regional Brain Aging in Huntington's Disease Using Structural Magnetic Resonance Imaging and Machine Learning

   Movement disorders : official journal of the Movement Disorder Society·24 Dec 2025

1. Regional brain age gap impairs cognitive function in humans.

   “A higher brain age gap in these regions was associated with declines in cognitive, motor, and functional performance.”

   Humansin persons with Huntington's diseasesubcortical, temporal, and parietal brain regions

   Mapping Regional Brain Aging in Huntington's Disease Using Structural Magnetic Resonance Imaging and Machine Learning

   Movement disorders : official journal of the Movement Disorder Society·24 Dec 2025

1. Psychological resilience is associated with regional brain age gap in humans.

   “Follow-up tests showed the CD-RISC x Group interaction was only significant in the subcortical region”

   Humanssubcortical region, in women with PTSDsubcortical regionfemales

   The moderating role of psychological resilience on brain aging and PTSD in a community sample of South African women

   Neuroscience·9 Feb 2026

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