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FoxO3A/SIRT3/mtRNAPol complex

Biomarker

1 paper1 finding

  • Cells1

Interventions

1

Caloric restriction

upin cells1

1 study

  1. Caloric restriction increases FoxO3A/SIRT3/mtRNAPol complex in cells.

    “A low-glucose regimen induces the formation of a protein complex containing FoxO3A, SIRT3, and mitochondrial RNA polymerase (mtRNAPol) at mitochondrial DNA-regulatory regions”

    Cellsin fibroblasts and skeletal myotubes

    A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels

    Cellular and molecular life sciences : CMLS3 Jan 2013

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