There are 6 papers on follistatin/myostatin ratio in aging research: 5 trials in people, 1 in animals.
6 papers study it6 findings
See all 6 papers on follistatin/myostatin ratio
- Human trial5
- Animals1
Interventions
3(+)-epicatechin
upin humans1upin mice1
2 studies
(+)-epicatechin
upin humans1upin mice1
(+)-epicatechin increases follistatin/myostatin ratio in humans (49.2 ± 16.6 %).
“Treatment for 7 days with Epi yielded a bilateral increase in hand strength of ~7% which was accompanied by a significant increase (49.2 ± 16.6 %) in the ratio of plasma follistatin/myostatin levels (data not shown).”
Human trial7 daysn = 6
Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation
The Journal of nutritional biochemistry
(+)-epicatechin increases follistatin/myostatin ratio in humans.
“Treatment for 7 days with (-)-epicatechin increases hand grip strength and the ratio of plasma follistatin/myostatin.”
Human trialplasma7 days
Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation
The Journal of nutritional biochemistry
(+)-epicatechin increases follistatin/myostatin ratio in mice (high-fat diet-induced decline in physical activity).
“The beverage and (-)-epicatechin increased the follistatin/myostatin ratio”
Animalshigh-fat diet-induced decline in physical activitypure5 wk
Food bioscience
Resistance training + essential amino acids
upin humans1+114%
1 study
Resistance training + essential amino acids
upin humans1+114%
Resistance training + essential amino acids increase follistatin/myostatin ratio in humans (compared with control and EAA groups) (F(3, 72) = 5.556, p = 0.002, partial η2 = 0.188).
“The follistatin/myostatin ratio increased most in the RE + EAA group (F(3, 72) = 5.556, p = 0.002, partial η2 = 0.188)”
Human trialcompared with control and EAA groups12 weeksfemales
Journal of the International Society of Sports Nutrition
Resistance training + essential amino acids increase follistatin/myostatin ratio in humans (+113.94%).
“Post-hoc comparisons demonstrated that the RE + EAA group exhibited a significantly greater increase in the ratio compared with both the CON (p < 0.001) and EAA groups (p < 0.05).”
Human trial12 weeksfemalesn = 96
Journal of the International Society of Sports Nutrition
Theobroma cacao flavanols
upin mice1
1 study
Theobroma cacao flavanols
upin mice1
Theobroma cacao flavanols increase follistatin/myostatin ratio in mice (high-fat diet-induced decline in physical activity).
“The beverage and (-)-epicatechin increased the follistatin/myostatin ratio”
Animalshigh-fat diet-induced decline in physical activitycocoa beverage enriched with flavanols5 wk
Food bioscience