Follistatin

Biomarker

4 papers3 findings

MeSH D038681

  • Human trial3
  • Humans1

Interventions

2

Akkermansia muciniphila

upin humans1

1 study
  1. Akkermansia muciniphila increases follistatin in humans (p = 0.0063).

    “HB05P notably elevated follistatin levels, which counteract myostatin, relative to the placebo group (p = 0.0063).”

    Human trialpasteurized1.0 × 1010 cells/day12-weekn = 100

    Pasteurized Akkermansia muciniphila HB05 (HB05P) Improves Muscle Strength and Function: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    Nutrients26 Nov 2024

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Dash diet

no changein humans1

1 study
  1. Dash diet has no effect on follistatin in humans.

    “There was no change (p > 0.05) in circulating follistatin concentrations in response to the diet intervention.”

    Human trial12 weeks

    Decreased myostatin in response to a controlled DASH diet is associated with improved body composition and cardiometabolic biomarkers in older adults: results from a controlled-feeding diet intervention study

    BMC nutrition15 Mar 2022

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Associations

1

Diabetes

upin humans1

1 study
  1. Diabetes is associated with follistatin in humans.

    “Activin A and follistatin levels were elevated in diabetes.”

    Humansn = 470

    Increased activin A levels in prediabetes and association with carotid intima-media thickness: a cross-sectional analysis from I-Lan Longitudinal Aging Study

    Scientific reports2 Jul 2018

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Latest

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bioRxiv

A protein promoted hair cell regeneration in newborn mice

Genetically modified newborn mice produced extra TRIM71, a protein that binds RNA, which promoted spontaneous regrowth of sound-detecting cells in the inner ear.Genetically modified newborn mice produced extra TRIM71, a protein that binds RNA, which promoted spontaneous regrowth of sound-detecting cells in the inner ear.

Preprint: experiments in miceEar