International Immunopharmacology
Salidroside alleviates senile osteoporosis in SAMP8 mice by inhibiting the ferroptosis of bone marrow stromal cells via PI3K/AKT/mTOR signaling pathway
Experiments in miceSenile osteoporosis
Papers on Factor 2
714 papers28 new in 30 days
Monday, October 20
Thursday, October 16
Diabetology & Metabolic Syndrome
Marine nutraceuticals as a source of SIRT1 and NRF2 activators for diabetes and aging-related metabolic disorders
ReviewInterventions
Monday, October 13
Journal of Diabetes and Metabolic Disorders
Amino acid metabolic signatures of dynapenic obesity in older adults: a (principal component analysis) PCA-based sex-stratified analysis in the Bushehr elderly health program
Cross-sectional study of 1,928 peopleDynapenia
Journal of Advanced Research
MK8722 alleviates osteoarthritis by activating Sesn2 and transcriptionally upregulating BNIP3 to promote mitophagy and inhibit chondrocyte ferroptosis
Experiments in miceOsteoarthritis
Saturday, October 11
Inflammopharmacology
Nrf2 signaling in bone health: unlocking new avenues for osteoporosis management
ReviewMAPK/ERK signaling
Wednesday, October 8
Wednesday, October 1
The International Journal of Neuropsychopharmacology
Mechanism of the AMPK/SIRT1 pathway in gut dysbiosis-mediated postoperative cognitive dysfunction in aged mice
Experiments in miceGut dysbiosis
Monday, September 29
American Journal of Physiology Cell Physiology
Protection of the human aortic valve interstitial cells against radiation-induced remodeling by repression of the TRPM4 channel
Experiments in miceMechanisms
Friday, September 26
Aging Cell
Enhancing Late-Life Survival and Mobility via Mitohormesis by Reducing Mitochondrial Calcium Levels
Experiments in wormsMitochondrion
Monday, September 22
Neurobiology of Disease
PKR-driven ISR signaling controls synaptic translation and structural plasticity in an age-dependent manner
Experiments in animalsSynapse
Friday, September 19
Monday, September 15
Saturday, September 13
Thursday, September 11
Frontiers in Neuroscience
Plasma FGF2 and YAP1 as novel biomarkers for MCI in the elderly: analysis via bioinformatics and clinical study
Case-control study in peopleBiomarkers
Sunday, August 31
World Journal of Critical Care Medicine
Klotho: A multifaceted protector in sepsis-induced organ damage and a potential therapeutic target
ReviewSepsis
Saturday, August 30
International Journal of Molecular Sciences
A Reassessment of Sarcopenia from a Redox Perspective as a Basis for Preventive and Therapeutic Interventions
ReviewSarcopenia
Thursday, August 28
Reproductive Sciences
Liquiritigenin Restores Declined Oocyte Quality and Improves Embryo Development in Aged Mice
Experiments in cellsInterventions
Thursday, August 14
Brain Research Bulletin
Increased DNA methylation of Igf2 in the male hippocampus regulates age-related deficits in synaptic plasticity and memory
Experiments in ratsDNA methylation
Saturday, August 9
International Ophthalmology
miR-24-3p mediates Keap1/Nrf2 axis to promote autophagy and thereby inhibit lens epithelial cell early senescence
Study of 30 peopleNRF2–KEAP1 antioxidant response
Thursday, August 7
Wednesday, July 30
International Journal of Urology
Silicon-Based Agent Attenuates Age-Related Spermatogenesis Disorder
Experiments in miceInterventions
Monday, July 28
Translational Neurodegeneration
Long-term exercise enhances meningeal lymphatic vessel plasticity and drainage in a mouse model of Alzheimer's disease
Experiments in miceExercise
Friday, July 25
International Journal of Molecular Medicine
Dulaglutide markedly prevents peritoneal fibrosis in a rodent model of chronic kidney disease: Insights into the pathogenesis
Experiments in ratsDulaglutide
Tuesday, July 22
Journal of Neuroimmunology
Fisetin alleviates Aβ-induced neuronal cell ferroptosis by regulating Sirt6-mediated deacetylation modification
Experiments in mouse cellsFisetin
Wednesday, July 9
Science Advances
Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis
Experiments in human cellsMuscle
Wednesday, July 2
Saturday, June 28
Journal of Molecular Neuroscience
Fisetin Attenuates Mutant SOD1 Aggregation in Amyotrophic Lateral Sclerosis via Nrf2-Mediated Autophagy Activation
Experiments in cellsFisetin