Expression of genes linked to cellular dysfunction and suppressed immune function

Biomarker

1 paper1 finding

  • Human trial1

Interventions

1

High-intensity knee-extension exercise

downin humans1

1 study
  1. High-intensity knee-extension exercise decreases expression of genes linked to cellular dysfunction and suppressed immune function in humans.

    “acute exercise attenuated these age-related differences by downregulating the genes related to those pathways.”

    Human trialAge-related gene expression differencesperipheral blood mononuclear cellSingle boutImmediately after exercise

    Transcriptomic analyses of peripheral blood mononuclear cells reveal age-specific basal and acute exercise responsiveness differences in humans

    American journal of physiology. Endocrinology and metabolism22 Jul 2025

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