4 papers
National Institute of Diabetes and Digestive and Kidney DiseasesUS$324.7kNational Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$1.3mNational Institute on AgingUS$859.5k
Aging, Sex Bias, and CD8 T Cell Exhaustion in Salivary Gland Inflammation
National Institute of Dental and Craniofacial ResearchOklahoma Medical Research FoundationUS$468.9k2025–2027
Genomic Instability as A Driver of Stem Cell Exhaustion
National Institute on AgingUniversity of California Los AngelesUS$424.1k2023–2028
National Institute of Arthritis and Musculoskeletal and Skin DiseasesSanford Burnham Prebys Medical Discovery InstituteUS$619.8k2021–2027
National Institute of Diabetes and Digestive and Kidney DiseasesUniversity of California-irvineUS$90.8k2022–2025
Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated connective-tissue cells.Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated connective-tissue cells.
Across both cohorts, the odds ratio for frailty was 0.52 when comparing Spanish older adults in the highest versus lowest third of diet scores.Across both cohorts, the odds ratio for frailty was 0.52 when comparing Spanish older adults in the highest versus lowest third of diet scores.
A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.
Researchers identified a conserved neural progenitor pool that drives weekly brain regeneration in Botryllus schlosseri but collapses during aging.Researchers identified a conserved neural progenitor pool that drives weekly brain regeneration in Botryllus schlosseri but collapses during aging.