Epigenetic markers

Biomarker

4 papers1 finding

Humans1
Animals1

Interventions

Yamanaka factors gene therapy

downin mice1

1 study

Yamanaka factors gene therapy decreases epigenetic markers in mice.
“This enhancement is closely tied to increased neuronal activation in regions related to memory processes, reversed aging-related epigenetic markers”
Animals
In vivo cyclic overexpression of Yamanaka factors restricted to neurons reverses age-associated phenotypes and enhances memory performance
Communications biologyMay 24, 2024

Funding

1 grant since 2022

National Institute on AgingUS$154k

Epigenetic markers, functional status, and exercise in older adults with myeloid neoplasms
National Institute on AgingUniversity of RochesterUS$154k2022–2024

Latest

20 in 12 months

International Journal of Molecular SciencesYesterday

Evolutionary Epigenetic Analysis of Oxidative Balance Score-Associated DNA Methylation Sites Across Mammals

Cross-sectional study in peopleDNA methylation

Paper

Aging and DiseaseSep 30

Older adults with preserved cognition show slower biological aging and longer telomeres

An observational study in Chile linked perfect Mini-Mental State Examination scores in people over 80 to slower epigenetic clocks and longer estimated telomeres.An observational study in Chile linked perfect Mini-Mental State Examination scores in people over 80 to slower epigenetic clocks and longer estimated telomeres.

Cross-sectional study of 80 peopleBiomarkers

Paper

Frontiers in OncologySep 11