Enzymes

Papers on enzymes

6,853 papers178 new in 30 days

Sunday, September 20

Friday, September 18

Prostaglandins & Other Lipid Mediators

Caloric restriction reshapes liver lipid profiles in mice

Caloric restriction across adulthood and aging blunted mid-life inflammatory surges in mouse livers and preserved fatty acid mediators compared with unrestricted feeding.Caloric restriction across adulthood and aging blunted mid-life inflammatory surges in mouse livers and preserved fatty acid mediators compared with unrestricted feeding.

Thursday, September 17

Nature Communications

Protein fragment extended life in mice with premature aging

Median survival rose from 95 days in controls to 115 days in mice given a peptide designed to stabilize a protein involved in DNA packaging.Median survival rose from 95 days in controls to 115 days in mice given a peptide designed to stabilize a protein involved in DNA packaging.

HMGA1 positively regulates HP1β in both HGPS and natural aging.
Mouse studyInterventions

Wednesday, September 16

Science Advances

Excess proteins in blood vessel cells shortened life in mice

Increasing either of two proteins accelerated vascular aging, while removing one extended lifespan in mice engineered to overproduce the other.Increasing either of two proteins accelerated vascular aging, while removing one extended lifespan in mice engineered to overproduce the other.

Endothelial C/EBPβ/AEP increases with age in human and mice.
Mouse studyMechanisms

Tuesday, September 15

Monday, September 14

Sunday, September 13

Friday, September 11