Papers on enzymes

6,865 papers179 new in 30 days

Monday, August 31

ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGEAug 31

Evaluation of Pro Inflammatory Cytokines and Genetic Polymorphismin Postmenopausal Bone Loss

Cross-sectional study of 81 peopleInflammation

Paper

Saturday, August 29

Current MicrobiologyAug 29

Protective Effect of Astaxanthin on Yeast Cells with Defects in Mitochondrial Function under Oxidative Stress and Aging

Experiments in yeastInterventions

Paper

Frontiers in AgingAug 29

Proteomics of aging: biomarkers for physiological systems and diseases

Conceptual framework of shared circulating proteomic aging modules linking multisystem decline to biological and clinical aging outcomes.

ReviewBiomarkers

Paper

Angewandte ChemieAug 29

Identification of Senescence-Associated β-Galactosidase With Single-Molecule Resolution

Experiments in human cellsSenescence-associated beta-galactosidase

Paper

Friday, August 28

Diabetes Research and Clinical PracticeAug 28

International consensus recommendations for smoking cessation in type 2 diabetes from the DiaSmokeFree Working group

ReviewIndustry & policy

Paper

JACC Basic to Translational ScienceAug 28

SGLT2-Inhibitors and Molecular Signatures of Aortic Valve Remodeling in Severe Aortic Stenosis: The Valve-AS Study

Cohort study of 83 peopleSGLT2 inhibitors

Paper

Ageing Research ReviewsAug 28

Intracranial aneurysms as a manifestation of premature vascular aging: Cellular senescence, inflammaging, and wall degeneration

ReviewCellular senescence

Paper

Thursday, August 27

Cell ReportsAug 27

An in vivo resource of age-regulated C. elegans intestinal secretory-pathway proteins highlights secreted enzymes associated with lifespan regulation

Experiments in wormsGut and microbiome

Paper

Research and Practice in Thrombosis and HaemostasisAug 27

Association between cardiorespiratory fitness and risk of incident venous thromboembolism: a prospective cohort study

Restricted cubic spline curves for the associations of cardiorespiratory fitness with venous thromboembolism.

Cohort study of 63,755 peopleVenous thromboembolism

Paper

Frontiers in ImmunologyAug 27

Trained immunity in gout: epigenetic and metabolic reprogramming of innate immune memory

A comprehensive schematic illustrating the metabolic and epigenetic pathways underlying trained immunity.

ReviewEpigenetic regulation of gene expression

Paper

NutrientsAug 27

Medicinal Plant Polysaccharides as Microbiota-Directed Modulators of Immunosenescence: Structural Determinants, Metabolite Reprogramming, and Host Immune Regulation

Schematic illustration of the structure–microbiota–metabolite–immunity axis through which MPPs may function as microbiota-directed modulators of immunosenescence.

ReviewTryptophan–kynurenine metabolism

Paper

International Journal of Molecular SciencesAug 27

Duration of Caloric Restriction Modulates Brain Redox Adaptation and Frailty During Aging

Individual body weight trajectories of male rats in the different dietary groups.

Experiments in ratsDietary restriction

Paper

International Journal of Molecular SciencesAug 27

DNA Methylation as a Programmable Information Layer: From Molecular Marks to Disease State Engineering

DNA methylation as a programmable information layer across biological scales.

ReviewDNA methylation

Paper

AntioxidantsAug 27

Seminal Vesicle Abnormalities and Exploratory miR-664-5p and FOXO Findings in Aged Mice Following Long-Term Butyl Benzyl Phthalate Exposure

Experimental design, physiological measures, and gross seminal vesicle findings.

Experiments in miceFOXO signaling

Paper

Nursing Edição BrasileiraAug 27

Statin-Related Cataract

Systematic reviewStatins

Paper

Wednesday, August 26

MetabolitesAug 26

Biomarkers in Obesity-Related Metabolic Syndrome: Relationships Between LDL Subfractions, Lipid Profile, and Cardiometabolic Risk in a Slovak Population

Cross-sectional study of 188 peopleMetabolic syndrome

Paper

MetabolitesAug 26

Association of M2BPGi with Subclinical Atherosclerosis in Metabolic Dysfunction-Associated Steatotic Liver Disease

Cross-sectional study of 6,514 peopleAtherosclerosis

Paper

Cell Biochemistry and BiophysicsAug 26

The Reductive Stress Nexus: Integrated Pathways of Metabolic Dysregulation, Senescence and Blood-Brain Barrier Failure in Neurodegenerative Disease and Brain Aging

ReviewNAD+ metabolism

Paper

CellsAug 26

Potential Roles of Cellular Senescence and Inflammaging in Prostate Cancer: Aging Microenvironment, Immune Remodeling, and Therapeutic Implications

Aging-associated senescence and inflammaging in the prostate tumor microenvironment.

ReviewExtracellular matrix remodeling

Paper

Jurnal Keperawatan Mandira CendikiaAug 26

Effect of Administering Aromatherapy From Eco Enzyme Extract on Sleep Quality in Older Adults in the Service Area of Tanjung Agung Palik Community Health Center, North Bengkulu Regency, in 2026

Non-randomized trial in 45 peopleInterventions

Paper

Tuesday, August 25

Environmental PollutionAug 25

Cadmium-associated cognitive impairment in adults: Proteomics-guided blood-based risk stratification with external validation and rat multimodal corroboration

Cohort study of 198 peopleCognitive impairment

Paper

Diabetes Research and Clinical PracticeAug 25

Efficacy of dapagliflozin on hepatic steatosis and fibrosis in patients with type 2 diabetes mellitus and metabolic dysfunction-associated steatotic liver disease: a pre-specified single-arm analysis from a randomized controlled trial

Non-randomized trial in 54 peopleDapagliflozin

Paper

Aging CellAug 25

DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca²⁺ Signaling

DHCR24 was down‐regulated in ATM‐mediated DNA damage response.

Experiments in human cellsDNA damage response

Paper

Journal of Nutrition and MetabolismAug 25

Meal Replacement Provides Additional Benefits for Weight and Visceral Fat Reduction in Prediabetic Individuals: A Randomized Clinical Trial

Randomized trial in 100 peopleInterventions

Paper

Frontiers in PharmacologyAug 25

Metabolic remodeling and cardiac functional adaptation mediated by dapagliflozin in patients with acute heart failure: a retrospective cohort study

Study flowchart of patient selection, propensity score matching, treatment, follow-up, and outcome assessment in a retrospective cohort of acute heart failure patients treated with dapagliflozin.

Cohort study of 50 peopleDapagliflozin

Paper

bioRxivAug 25

ALDH Activity in Monocytes is Associated with Subclinical Coronary Atherosclerosis in Treated People with HIV-1

Characterization of ALDH activity in PBMCs of CHACS participants using the ALDEFLUOR assay and unsupervised flow cytometry analysis.

Preprint: cohort study in peopleCoronary atherosclerosis

Paper

Monday, August 24

Arthritis & RheumatologyAug 24

Interleukin-12 Signaling Promotes Podocyte Senescence in Lupus Nephritis

Experiments in miceJAK–STAT signaling

Paper

bioRxivAug 24

Gut Microbiome Composition in Older Adults with PTSD Symptoms and Trauma-Exposed Controls: Findings from the GUMP Study

Associations between PTSD symptom severity, age, and selected cognitive performance measures.

Preprint: cohort study in peopleGut and microbiome

Paper

Sunday, August 23

medRxivAug 23

Association between DNMT3A-driven clonal hematopoiesis, trained immunity and immune cell function in obesity

Consort diagram depicting the inclusion of individuals based on CHDMs identified in 2016 and 2023, final groups(No CHDM, DNMT3A) are included in the current study.

Preprint: cohort study in peopleImmune response

Paper

Saturday, August 22

Journal of BiomechanicsAug 22

Older mouse tendons responded poorly to repeated compression

A seven-day laboratory experiment compared responses to repeated squeezing in tendons from 32 young and 36 aged male mice.A seven-day laboratory experiment compared responses to repeated squeezing in tendons from 32 young and 36 aged male mice.

Experiments in mouse cellsMechanisms

Paper