Papers on enzymes

6,948 papers184 new in 30 days

Saturday, August 22

Neuropharmacology and TherapyAug 22

Polyamine Metabolism in Brain Health and Disease

ReviewMechanisms

Paper

Advanced Functional MaterialsAug 22

Mechano‐Electrical Coupling Scaffold Drives Bone Organoids Bioenergetic Reprogramming to Accelerate Bone Regeneration

Experiments in ratsBones and joints

Paper

Friday, August 21

Mechanisms of Ageing and DevelopmentAug 21

Puerarin extends lifespan and enhances the resistance to oxidative stress through AMPK/TFEB mediated autophagy in Caenorhabditis elegans

Figure from Mechanisms of Ageing and Development

Experiments in wormsInterventions

Paper

Redox BiologyAug 21

Dynamics of blood NAD and glutathione in health, disease, aging, and under NAD⁺-booster treatment

Trial in peopleNAD+ precursors

Paper

Journal of Clinical HypertensionAug 21

Renin-Angiotensin System Inhibitor Use and Mortality in Older Hypertensive Patients With and Without Dementia: A Nationwide Registry-Based Cohort Study

Cohort study of 158,176 peopleDementia

Paper

Next MaterialsAug 21

Peroxidase mimicking nanozyme catalyzed colorimetric immunosensor for detection of osteoporosis biomarker CTX-1

Study in peopleOsteoporosis

Paper

Thursday, August 20

Methods in EnzymologyAug 20

ChIPmentation-based mapping of histone modifications in aging: Experimental design and analytical considerations

Study protocolMechanisms

Paper

Frontiers in EndocrinologyAug 20

SHBG and APOA1 as serum biomarkers for low bone mineral density in Mexican postmenopausal women: a random forest-based analysis

The comparison of serum concentrations of RYR1, SHBG, APOA1, APOA2, GSN, and RYR3 proteins between the NBMD and LBMD groups.

Cross-sectional study of 456 peopleSHBG

Paper

bioRxivAug 20

NAMPT activation uncovers a senescence-specific vulnerability and promotes healthy aging in combination with NAM

Accumulation of NAMPT in senescent cells is accompanied by reduced rates of NAD+ synthesis and consumption.

Preprint: experiments in miceInterventions

Paper

Wednesday, August 19

Journal of Diabetes and Its ComplicationsAug 19

Clinical efficacy of switching to tirzepatide in patients with type 2 diabetes and a high risk of metabolic dysfunction-associated steatotic liver disease undergoing GLP-1 receptor agonist therapy: Insights from the Hokkaido-TZP study

Figure from Journal of Diabetes and Its Complications

Cohort study of 182 peopleGLP-1 receptor agonists

Paper

Science AdvancesAug 19

A bacterial enzyme enhances both energy metabolism and health across the life span of C. elegans and mice

mitoLplA increases lipoylation level and PDH activity in C. elegans.

Experiments in wormsInterventions

Paper

Journal of Visualized ExperimentsAug 19

Mollugin Supports Zebrafish Tail Regeneration in Association with Altered Inflammatory and Oxidative Responses

Experiments in zebrafishInterventions

Paper

Nature CommunicationsAug 19

Muscle-derived molecule improves exercise performance in mice

In mouse experiments, six weeks of a muscle-derived molecule increased voluntary running and enhanced the muscle benefits of exercise training.In mouse experiments, six weeks of a muscle-derived molecule increased voluntary running and enhanced the muscle benefits of exercise training.

BAIBA induces an exercise training-like effect on exercise performance and skeletal muscle function in vivo.

Mouse studyMuscle

Paper

Tuesday, August 18

Journal of Visualized ExperimentsAug 18

Liuwei Dihuang Wan Inhibits Osteoclastogenesis and Ovariectomy-Induced Bone Loss by Suppressing NF-κB Signaling

Experiments in 27 miceBones and joints

Paper

Journal of Visualized ExperimentsAug 18

CRISPR/Cas9-Mediated Generation and Characterization of an Ent2/CyO Drosophila melanogaster* Strain

Experiments in fliesMechanisms

Paper

Diabetes, Metabolic Syndrome and ObesityAug 18

Serum GDF3 is Associated with Visceral Obesity, Insulin Resistance, and Inflammation in Non-Diabetic Adults: A Cross-Sectional Study with an Interventional Component

Comparison of serum GDF3 levels between non-visceral obesity and visceral obesity.

Cross-sectional study of 282 peopleVisceral obesity

Paper

Cell Biochemistry and FunctionAug 18

TET2 as a Context-Dependent Epigenetic Integrator in Clonal Hematopoiesis, Inflammation, Cancer, and Immunotherapy

ReviewInflammation

Paper

Monday, August 17

Ageing Research ReviewsAug 17

NAD⁺ circuits in aging, tissue repair and fibrosis

ReviewMechanisms

Paper

Saturday, August 15

iScienceAug 15

Older mouse muscle contained less of a compound called spermidine

Gene-activity mapping in muscle from three young and four old mice revealed changes in the machinery that produces this compound.Gene-activity mapping in muscle from three young and four old mice revealed changes in the machinery that produces this compound.

Cross-sectional studyMuscle

Paper

Friday, August 14

European Geriatric MedicineAug 14

Circulating biomarkers of the brain-muscle-metabolic axis in primary sarcopenia: neudesin, nesfatin-1, and irisin

Cross-sectional study of 88 peopleIrisin

Paper

Advanced Healthcare MaterialsAug 14

3D-Printable and Bioelectronic-Compatible Graphene-Reinforced PLA Nanocomposites Rejuvenate Aged Bone Regeneration Through Glycolytic Reprogramming

Figure from Advanced Healthcare Materials

Experiments in ratsBones and joints

Paper

Thursday, August 13

Zhonghua Xin Xue Guan Bing Za ZhiAug 13

Gastrointestinal metabolic surgery improves salt-sensitive hypertension via GLP-1-mediated inhibition of the RAS/NHE3 axis

Experiments in 48 ratsHypertension

Paper

Molecular NeurobiologyAug 13

Associations of Iron Indicators with Cognitive Impairment Risk in Postmenopausal Women: Evidence from a Matched Case-Control Study and Back Propagation Neural Network Model

Case-control study of 1,344 peopleCognitive impairment

Paper

NutrientsAug 13

Phycocyanobilin Attenuates Oligomerized Amyloid β-Induced Neuronal Senescence Through SIRT1-Associated Mechanisms

Protective effects of phycocyanobilin (PCB) against amyloid-β (Aβ)1–42 oligomer-induced cytotoxicity in SH-SY5Y cells.

Experiments in human cellsInterventions

Paper

CellsAug 13

Reducing a protein lowered inflammatory signals in human disc cells

Experiments using cells from four donors found lower activity of inflammatory genes and higher activity of genes associated with the supporting material around cells.Experiments using cells from four donors found lower activity of inflammatory genes and higher activity of genes associated with the supporting material around cells.