Papers on enzymes

6,949 papers184 new in 30 days

Tuesday, August 11

Clinical TherapeuticsAug 11

Cardiovascular Outcomes in Middle-Aged Adults on Antihypertensive Medications and No Prior Cardiovascular Disease

Cohort study of 217,617 peoplePopulations

Paper

Molecular Biology ReportsAug 11

Effect of Glycosylphosphatidylinositol-specific phospholipase D1 knockout on the expression of antioxidant enzymes and sirtuin

Experiments in mouse cellsSirtuin signaling

Paper

Vascular Health and Risk ManagementAug 11

Malondialdehyde-Superoxide Dismutase Redox Imbalance as an Early Biological Risk Indicator in Young Adult Smokers

Cross-sectional study of 190 peopleMalondialdehyde

Paper

Experimental and Therapeutic MedicineAug 11

Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis in vitro

Experiments in human cellsInterventions

Paper

MetabolismAug 11

HSF1-UCHL1 transcriptional axis protects against MASLD via regulation of PPARα protein stability

Experiments in miceHeat shock response and chaperones

Paper

Journal of South Asian Federation of Obstetrics and GynaecologyAug 11

The Estrobolome and Gut Microbiome in Perimenopause: Bidirectional Interactions, Clinical Consequences, and Therapeutic Opportunities

ReviewGut and microbiome

Paper

Saturday, August 8

Preprints.orgAug 8

Pro-Inflammatory and Anti-Inflammatory Cytokines in Older Men Participating in an Aquatic Exercise Programme and a Multicomponent Exercise Programme: A Cross-Sectional Exploratory Study

Preprint: cross-sectional study of 15 peopleAquatic exercise

Paper

BioinformaticsAug 8

hypeR-GEM: connecting metabolite signatures to enzyme-coding genes via genome-scale metabolic models

Computational studyAI & data

Paper

Frontiers in ImmunologyAug 8

Aerobic exercise combined with FK866 ameliorates Alzheimer's disease-like pathology in APP/PS1 mice with NAMPT abnormality

Experiments in miceAerobic exercise

Paper

Friday, August 7

Zhurnal Nevrologii I Psikhiatrii Imeni S.S KorsakovaAug 7

Clusterin as a biomarker for Alzheimer's disease

Systematic reviewAlzheimer's disease

Paper

Thursday, August 6

Biomedical and Environmental SciencesAug 6

Concurrent MASLD and Long-term Outcomes in HBV-infected Individuals: A Population-based Cohort Study

Cohort study of 120,913 peopleMetabolic dysfunction-associated steatotic liver disease

Paper

The World Journal of Men's HealthAug 6

Sex-Specific Associations of Helicobacter pylori Seropositivity and Intestinal Metaplasia with Colorectal Adenoma: A Korean Multicenter Cross-Sectional Study

Cross-sectional study of 806 peopleColorectal adenoma

Paper

Wednesday, August 5

Advanced ScienceAug 5

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Experiments in miceCellular senescence

Paper

Renal FailureAug 5

Prevention of new-onset chronic kidney disease with renin-angiotensin system blockers in type 2 diabetes with preserved kidney function

Cohort study of 316,693 peopleChronic kidney disease

Paper

Coordination Chemistry ReviewsAug 5

Antioxidant nanozymes for regenerative medicine: mechanisms, design, and applications in tissue repair

ReviewInterventions

Paper

bioRxivAug 5

Locus-specific transposable element expression drives human hematopoietic stem cell disease pathophysiology

Preprint: experiments in human cellsTransposable element activity

Paper

Tuesday, August 4

Research SquareAug 4

White matter impairment as an early signature of incident dementia

Preprint: cohort study in peopleAll-cause dementia

Paper

PelviperineologyAug 4

Standards of care and future directions in vaginal atrophy

ReviewInterventions

Paper

Monday, August 3

DiabetesAug 3

Adipose Tissue Palmitoylation Cycling Mediates Insulin Resistance and Preservation of β-Cell Function in Mice

Experiments in miceMechanisms

Paper

Experimental & Molecular MedicineAug 3

Neddylation of NFATc1 and Runx2 regulates osteoclast-osteoblast balance and represents a dual-action therapeutic target for postmenopausal osteoporosis

Experiments in miceNFATC1

Paper

Zhongguo Zhong Yao Za ZhiAug 3

Construction of a long-lived engineered yeast and its efficient catalytic synthesis of ursodeoxycholic acid

Experiments in yeastMechanisms

Paper

ACS Applied Nano MaterialsAug 3

Immune-Phase-Aware Protein Delivery via Polymeric Nanomedicines for Tissue Regeneration: A Review

ReviewBlood and immune system

Paper

Sunday, August 2

medRxivAug 2

GLP1R Variants and Polygenic Risk Underlie Heterogeneous Response to GLP-1 Receptor Agonists in Type 2 Diabetes

Preprint: cohort study of 5,784 peopleGLP-1 receptor agonists

Paper

Indian Journal of Endocrinology and MetabolismAug 2

Calcium Supplementation in the Indian Context: A Consensus Statement by the Endocrine Society of India Skeletal Health Taskforce

ReviewIndustry & policy

Paper

Journal of Orthopaedic TranslationAug 2

Ganoderic acid A accelerates osteoporotic fracture healing by promoting osteogenic differentiation via estrogen receptor alpha binding

Experiments in miceOsteoporotic fractures

Paper

Saturday, August 1

Journal of Clinical LipidologyAug 1

Efficacy and safety of inclisiran monotherapy in Chinese adults with elevated low-density lipoprotein cholesterol: Results from the VICTORION-Mono China trial

Randomized trial in 207 peopleInclisiran

Paper

Friday, July 31

AutophagyJul 31

Trr1 (thioredoxin reductase 1) modulates ERphagy in aging via liquid-liquid phase separation

Experiments in yeastMechanisms

Paper

CureusJul 31

Clinical Characteristics and In-Hospital Outcomes of Patients Aged 90 Years or Older Admitted to an Internal Medicine Department: A Single-Center Study From Portugal

Case series of 89 peoplePopulations

Paper

Nature Structural & Molecular BiologyJul 31

Protein thiol alterations drive pathologic liquid-liquid phase separation in the aging brain

Experiments in miceMechanisms

Paper

Ageing Research ReviewsJul 31

Beyond the barrier: Physiological determinants of nanoformulation availability in the aging brain

ReviewMechanisms

Paper