Dopaminergic neurons

2 papers

Animals2

Latest

29 in 12 months

Aging Cell11 Oct

Ginseng compound extended lifespan and preserved movement in worms

In worm experiments, the ginseng-derived compound also preserved touch sensitivity and restored age-impaired function in nerve cells’ waste-processing compartments.In worm experiments, the ginseng-derived compound also preserved touch sensitivity and restored age-impaired function in nerve cells’ waste-processing compartments.

Experiments in wormsInterventions

Research Square10 Oct

Alpha-synuclein pathology alters lipids in mice and human cells

In mouse midbrain and cultured human neurons, alpha-synuclein pathology led to shorter, more saturated lipid chains, an effect largely reversed in mice by intermittent…In mouse midbrain and cultured human neurons, alpha-synuclein pathology led to shorter, more saturated lipid chains, an effect largely reversed in mice by intermittent fasting.

Preprint: experiments in miceMechanisms

Neural Regeneration Research2 Oct

Crosstalk between exosomes and cellular senescence: A core vicious loop promoting α-synuclein pathology in Parkinson's disease

ReviewCellular senescence

Aging29 Sep

Hypomagnetic fields modulate lifespan, physical ability and mitochondrial metabolism in a Pink1 model of neurodegeneration

Experiments in fliesOxidative phosphorylation

Nature Communications22 Sep

Combinatorial mechanisms specify cellular location and neurotransmitter identity during planarian neurogenesis

Experiments in model organismsMechanisms

Aging and Disease3 Sep

Motor System Neurodegeneration in Aging and Synucleinopathies: Circuit Vulnerability and Neuroimaging Biomarkers

ReviewMechanisms

Aging Medicine (Milton (N.S.W))3 Sep

Shared Metabolic-Proteinopathy Axis in Alzheimer's Disease and Parkinson's Disease: Evidence for a Convergent but Not Identical Disease Spectrum

ReviewMechanisms

Antioxidants27 Aug

Mitochondrial Ca²⁺ Influx via MCU-1 Contributes to Oxidative Mitochondrial Defects in PDR-1/Parkin-Deficient Caenorhabditis elegans Body-Wall Muscle

Experiments in wormsMitochondrion

Frontiers in Aging Neuroscience18 Aug

Stereological sampling-based estimates of dopaminergic and cholinergic neuron numbers in young adult and aged male and female Fischer 344 × Brown Norway F1 hybrid rats

Experiments in ratsMechanisms

Scientific Reports18 Aug

Distinct media requirements for dopaminergic neuron reprogramming from human glia and fibroblasts

Experiments in human cellsInterventions