DNA repair gene expression
2 papers2 findings
- Model organisms1
- In silico1
Upstream
1lin-15B
upin worms1
1 study
lin-15B
upin worms1
lin-15B increases DNA repair gene expression in worms.
“Nuclear LIN-15B then activates a broad transcriptional program encompassing core UPRmt targets and a unique set of DNA repair genes.”
Model organismsFollowing nuclear translocation of LIN-15B
A Surveillance Pathway Senses Leaked Mitochondrial DNA to Activate UPRmt and Promote Longevity
Preprint13 Jan 2026Preprint
Associations
1Ovarian aging
downin humans1
1 study
Ovarian aging
downin humans1
Ovarian aging is associated with DNA repair gene expression in humans.
“Aging granulosa cells downregulated DNA repair genes and induced cell-cycle inhibitor genes across species”
Humansgranulosa cellfemales
Single-cell exploration of ovarian aging across mammalian models
bioRxiv (Cold Spring Harbor Laboratory)15 Oct 2025Preprint
Latest
3 in 12 monthsFrontiers in Sports and Active Living
The role of exercise in modulating NAD+ metabolic enzymes: mechanisms and health benefits
ReviewExercise
Preprint
A Surveillance Pathway Senses Leaked Mitochondrial DNA to Activate UPRmt and Promote Longevity
Preprint: experiments in wormsMitochondrion
Immunity & Ageing
Warmer temperature accelerates senescence by modifying the aging-dependent changes in the mosquito transcriptome, altering immunity, metabolism, and DNA repair
Experiments in model organismsDNA repair
Mutation Research Genetic Toxicology and Environmental Mutagenesis
Protective role of Cockayne Syndrome B (CSB) protein in maintaining genome integrity in human cells under oxidative stress
Experiments in human cellsOxidative stress and ROS signalling
bioRxiv
Single-cell exploration of ovarian aging across mammalian models
Preprint: computational studyReproductive system