Collagen gene expression

Biomarker

2 papers1 finding

Model organisms1
In silico1

Associations

Lifespan extension

upin worms1

1 study

Lifespan extension is associated with collagen gene expression in worms (in 84% of long-lived conditions).
“showed collagen upregulation in 84% of long-lived conditions, identifying collagen induction as a conserved signature of lifespan extension”
Model organismsin long-lived conditions
Collagen gene expression is linked to aging and lifespan extension in C. elegans
Matrix biology plus1 Mar 2026

Latest

3 in 12 months

Antioxidants26 Sep

Antipsychotic drug pimozide extends lifespan and boosts stress resistance in nematodes

The treatment relies on SKN-1 activation to increase collagen synthesis and enhance healthspan markers in Caenorhabditis elegans.The treatment relies on SKN-1 activation to increase collagen synthesis and enhance healthspan markers in Caenorhabditis elegans.

Experiments in wormsInterventions

Paper

Matrix Biology Plus11 Mar