Papers on clinical severity

Who was studied57,488 older adults at their first intensive care admission

What changedThe model scored 0.872 at distinguishing hospital deaths from survivors among older intensive care patients

The catchThe evaluations measured predictions, not whether using them improved survival or nutrition care

Who was studied16,027 Chinese adults aged 45–90 years, against people without each condition

What changedThinking scores were lower with stroke but higher with heart disease than without each condition

The catchDisease severity and duration could explain differences in thinking scores between conditions

Who was studied11,518 ancestrally diverse US adults, 26 years

What changedGenetic scores were associated with dementia risk through cognitive decline for some traits and through premorbid cognitive differences for others

The catchEffects of changing diabetes risk, physical activity, or other traits were not measured

Who was studied14,845 participants, against the non-obese group

What changedIncident cardiovascular disease risk was higher with clinical obesity than in the non-obese group (aHR 1.67)

The catchExisting clinical conditions in the definition confounded body fat's contribution to cardiovascular risk

Who was studiedPeople with facioscapulohumeral muscular dystrophy

What changedSenescence-related gene-activity patterns appeared even in patient muscles without inflammation visible on scans

The catchPatient findings used senescence-related gene-activity patterns as a proxy for cellular senescence

Who was studiedFemale C57BL/6NJcl mice, 25 weeks, against mice exposed to UVB alone

What changedSkin damage severity did not differ between NMN-treated mice and mice exposed to UVB alone

The catchOnly 6 mice per group limited detection of differences in skin damage

Who was studied360 adults aged ≥60 years, 10 years, against matched controls

What changedCognitive impairment affected 54% with diabetic retinopathy, 52% with glaucoma, and 49% with macular degeneration, versus 27% of controls

The catchEye-disease groups had less education, more depression, and more illness, potentially explaining the association

Who was studied1,645 adults across the Alzheimer disease spectrum

What changedImaging markers tracked clinical severity across healthy aging and Alzheimer disease

The catchThe abstract reports imaging markers tracking severity, but no treatment outcomes