What does the research say about clinical severity?

Clinical severity

There is 1 paper on clinical severity in aging research: 1 observational study in people. The newest story, Nov 12, 2026: “Model predicted hospital death risk in older intensive care patients”.

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18 new papers in 30 daysSee all 130 papers on clinical severity

Humans1

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57 papers in 12 months

Frontiers in NutritionNov 12

Model predicted hospital death risk in older intensive care patients

The updated model scored 0.872 at distinguishing hospital deaths from survivors among 57,488 older intensive care patients across 206 hospitals.The updated model scored 0.872 at distinguishing hospital deaths from survivors among 57,488 older intensive care patients across 206 hospitals.

Accepted, not yet published: cohort · 57,488 peopleBiomarkers

Paper

BMC Public HealthNov 11

Chronic diseases had different links to thinking scores

People with memory-related diseases scored 0.292 standard deviations lower on overall thinking tests than those without; standard deviations measure the spread of scores.People with memory-related diseases scored 0.292 standard deviations lower on overall thinking tests than those without; standard deviations measure the spread of scores.

Cohort · 16,027 peoplePopulations

Paper

Dementia and Neurocognitive DisordersNov 11

Association of Cholinesterase Inhibitor-Memantine Combination Therapy With Long-Term Community Management and Mortality in Patients With Dementia: A Nationwide Retrospective Cohort Study

Cohort study of 942,068 peopleDementia

Paper

medRxivNov 9

Genetic dementia risk linked to thinking levels and decline

An observational analysis of 11,518 US adults used 26 years of data to distinguish genetic links involving preexisting thinking ability from those involving age-related…An observational analysis of 11,518 US adults used 26 years of data to distinguish genetic links involving preexisting thinking ability from those involving age-related decline.

Preprint: cohort · 11,518 peopleAlzheimer's disease and related dementias

Paper

AHA Scientific Sessions 2026 AbstractNov 9

Beyond Statins: Real-World Long-Term Effectiveness of PCSK9 Inhibitors versus Ezetimibe in Atherosclerotic Cardiovascular Disease

Cohort study of 16,145 peoplePCSK9 inhibitors

Paper

AHA Scientific Sessions 2026 AbstractNov 7

Clinical obesity linked to higher cardiovascular disease risk

Under the new definition, people with obesity and clinical risk factors had higher cardiovascular risk than those without obesity, with an adjusted hazard ratio of 1.67.Under the new definition, people with obesity and clinical risk factors had higher cardiovascular risk than those without obesity, with an adjusted hazard ratio of 1.67.

Cohort · 14,845 peopleClinical obesity

Paper

AHA Scientific Sessions 2026 AbstractNov 7

Pre-Admission Statin Therapy and Circulatory Collapse at Hospital Arrival in ST-Segment Elevation Myocardial Infarction

Cohort study of 551 peopleST-elevation myocardial infarction

Paper

The Journal of Clinical InvestigationNov 5

Patient muscles show early signs of cell senescence

An analysis of patient muscle gene activity found senescence-related patterns linked to disease severity and present even without inflammation visible on scans.An analysis of patient muscle gene activity found senescence-related patterns linked to disease severity and present even without inflammation visible on scans.

Cross-sectional studyCellular senescence