Circulating IGF-1

Biomarker

1 paper1 finding

  • Animals1

Interventions

1

Lovastatin + ezetimibe

downin mice1

1 study
  1. Lovastatin + ezetimibe decreases circulating IGF-1 in mice.

    “in vivo lovastatin and ezetimibe (LE) exposure increased hepatic SA-β-gal-positive area, elevated p21/p16 expression, and lowered circulating IGF-1.”

    Animalsin vivo lovastatin and ezetimibe exposure

    Statin-exposed liver cells impaired muscle formation in the lab

    Cell death discovery10 Oct 2026

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Cell Death Discovery

Statin-exposed liver cells impaired muscle formation in the lab

Experiments with lab-grown liver and muscle cells linked statin exposure to lower levels of insulin-like growth factor-1, a growth signal.Experiments with lab-grown liver and muscle cells linked statin exposure to lower levels of insulin-like growth factor-1, a growth signal.

Experiments in animalsMuscle