Cell Research
Pain-sensing nerve cells limited kidney injury in mice
A signal released by these nerves acted on immune cells to limit inflammation after kidney blood flow was interrupted and restored in mouse experiments.A signal released by these nerves acted on immune cells to limit inflammation after kidney blood flow was interrupted and restored in mouse experiments.
Mouse studyKidney
Who was studiedFemale mice with ischemia-reperfusion kidney injury, against littermate control mice
What changedRemoving pain-sensing nerve cells worsened kidney injury in mice compared with littermate controls
The catchHigh mortality prevented adequate analysis of male mice, leaving formal experiments restricted to females