Atherogenic and inflammatory cytokine and chemokine expression

Senescent foamy macrophages increase atherogenic and inflammatory cytokine and chemokine expression in mice.

“they drive pathology by increasing expression of key atherogenic and inflammatory cytokines and chemokines”

Animalsonset of atherosclerosis in Ldlr-deficient micesubendothelial space

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

Science (New York, N.Y.)·Oct 27, 2016