2 papers2 findings
Racial discrimination
upin humans1
Racial discrimination increases cerebral amyloid in humans.
“Endorsing 2+ reasons was significantly associated with higher burden of cerebral amyloid among Black participants”
Humansin Black participants endorsing 2+ reasons
AAIC 2025 abstract25 Dec 2025
Dynamic light scattering spectroscopy
upin humans1
Dynamic light scattering spectroscopy predicts cerebral amyloid in humans (100% sensitivity, 83% specificity).
“DLS testing correctly identified all 10/16 (100%) of the patients that were positive for amyloid, and 5/6 (83%) patients that were negative for amyloid.”
Human trialin patients with mild cognitive impairment undergoing PET amyloid imagingn = 16
Earlier Diagnosis of Alzheimer’s Disease by Dynamic Light Scattering Spectroscopy of the Eye
AAIC 2025 abstract23 Dec 2025
In an observational study of 735 people, other brain vessel injuries strengthened links between shorter sleep and brain lesions in some diagnostic groups.In an observational study of 735 people, other brain vessel injuries strengthened links between shorter sleep and brain lesions in some diagnostic groups.
Over a median 5.1 years, bleeding-related lesions appeared in 33.7% of participants with severe enlargement versus 13.6% without severe enlargement.Over a median 5.1 years, bleeding-related lesions appeared in 33.7% of participants with severe enlargement versus 13.6% without severe enlargement.
In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.
In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status, with an adjusted…In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status, with an adjusted difference of −0.582.
In an autopsy study of 265 decedents, vessel mineralization appeared in 58.3% of globus pallidus samples, 28.6% of posterior hippocampus samples, and 13.8% of putamen…In an autopsy study of 265 decedents, vessel mineralization appeared in 58.3% of globus pallidus samples, 28.6% of posterior hippocampus samples, and 13.8% of putamen samples.
Lewy body disease prevalence rose from 0.7% in individuals younger than 50 to 20.0% in those aged 90 and older across 2,480 autopsied human brains.Lewy body disease prevalence rose from 0.7% in individuals younger than 50 to 20.0% in those aged 90 and older across 2,480 autopsied human brains.