Racial discrimination

6 papers13 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

4 independent labs in 1 country
1 finding against

Humans6

Outcomes

Enlarged perivascular spaces

downin humans1upin humans1

1 study

Racial discrimination decreases enlarged perivascular spaces in humans.
“Racial discrimination was significantly associated with smaller ePVS volumes in White participants, and larger ePVS volumes in Black participants”
Humansin White participants
Association of Lifetime Discrimination with Cerebral Small Vessel Disease and Amyloid PET: the Multi‐Ethnic Study of Atherosclerosis (MESA)
AAIC 2025 abstract25 Dec 2025
Racial discrimination increases enlarged perivascular spaces in humans.
“Racial discrimination was significantly associated with smaller ePVS volumes in White participants, and larger ePVS volumes in Black participants”
Humansin Black participants
Association of Lifetime Discrimination with Cerebral Small Vessel Disease and Amyloid PET: the Multi‐Ethnic Study of Atherosclerosis (MESA)
AAIC 2025 abstract25 Dec 2025

Associations

Cerebral microbleeds

upin humans1

1 study

Racial discrimination is associated with cerebral microbleeds in humans.
“Lifetime discrimination was associated with higher odds of CMB in Hispanic participants”
Humansin Hispanic participants
Association of Lifetime Discrimination with Cerebral Small Vessel Disease and Amyloid PET: the Multi‐Ethnic Study of Atherosclerosis (MESA)
AAIC 2025 abstract25 Dec 2025