CEBPB

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Blood5 Oct

Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia - the ECOG-ACRIN E1910 study

Cohort study of 569 peopleInterventions

Chemosphere9 Sep

Phthalate exposure and osteoporosis: NHANES associations and integrative in silico prioritization of candidate molecular targets

Cross-sectional study of 8,273 peopleOsteoporosis

npj Aging18 Jul

Systemic mapping of senescence characteristics across septic tissues

Computational studyCellular senescence

Nucleic Acids Research7 Jul

Enhancing the performance and interpretability of epigenetic clocks

Computational studyEpigenetic clock

bioRxiv8 Apr

Microglia as transcriptional pacemakers of neuronal aging heterogeneity across individuals

Preprint: computational studyMechanisms

BMC Genomics4 Feb

Integrated analysis of differential m6A methylation and transcriptome profiles in ovaries of young and aged Qira black sheep

Experiments in sheepReproductive system

Applied Biochemistry and Biotechnology9 Jan

TEAD4 and RXRA Regulate the Function of Nucleus Pulposus Cells in Intervertebral Disc Degeneration Via the TNF-α/NF-κB Pathway: An Integrated Analysis of Single-Cell RNA-Seq, Bulk RNA-Seq, and In Vitro Validation

Study in peopleTNF signalling

Redox Biology19 Dec

Rapamycin preserves cardiac function in autoimmune myocarditis by reprogramming Cxcl9⁺ macrophages via the mTORC1-C/EBPβ-OSM axis

Experiments in miceRapamycin

Clinical and Translational Medicine18 Nov

Spatiotemporal mapping reveals Ccl8hi macrophages as key drivers of testicular inflammaging

Experiments in miceInflammation

bioRxiv7 Oct

An improved epigenetic age estimation with TFMethyl Clock reveals DNA methylation changes during aging in transcription factor binding sites

Preprint: computational studyBiomarkers