CD11c

Protein loss promotes age-linked brain cell activation in mice

In experiments, aged mice lacking the protein showed stronger age-linked brain cell activation, but no obvious loss of nerve insulation or faster decline in movement.In experiments, aged mice lacking the protein showed stronger age-linked brain cell activation, but no obvious loss of nerve insulation or faster decline in movement.

Limit: The experiments did not distinguish adaptive activation from early, compensated persistent activation

Old lung environment changes immune cell traits in mice

One lung immune cell population increased more than 10-fold in old mice compared with younger mice.One lung immune cell population increased more than 10-fold in old mice compared with younger mice.

Exercise remodels muscle progenitor cells in older adults

Six weeks of blood flow restricted resistance exercise enlarged muscle progenitor cells and shifted fibro-adipogenic progenitors toward a pro-myogenic state in healthy…Six weeks of blood flow restricted resistance exercise enlarged muscle progenitor cells and shifted fibro-adipogenic progenitors toward a pro-myogenic state in healthy older adults.