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Cardiomyocyte

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Sex

mixedin humans1

1 study

  1. sex is associated with cardiomyocyte in humans.

    “alterations in abundance of cardiomyocytes by sex and neurons with age.”

    Humansheart

    Single-cell analysis of chromatin and expression reveals age- and sex-associated alterations in the human heart

    Communications biologyAug 26, 2024

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European Heart Journal Cardiovascular Pharmacotherapy

Dapagliflozin did not improve heart relaxation in small trial

A heart-relaxation measure stayed at 6.2 with dapagliflozin, versus 6.6 to 6.7 with placebo, in a 32-person randomised trial.A heart-relaxation measure stayed at 6.2 with dapagliflozin, versus 6.6 to 6.7 with placebo, in a 32-person randomised trial.

Randomized trial · 29 peopleDapagliflozin
Paper
Aging Cell

Restoring a protein partly improves heart function in mice

Experiments in mice producing a progeria-linked protein in heart muscle cells found that restoring an RNA-marking protein partly reduced abnormal heart changes.Experiments in mice producing a progeria-linked protein in heart muscle cells found that restoring an RNA-marking protein partly reduced abnormal heart changes.

Mouse studyMechanisms
Paper
Biochimica et Biophysica Acta Molecular Basis of Disease

Low cell-attachment protein levels linked to heart aging in mice

Mice with one working copy of the protein’s gene had enlarged, scarred hearts and poorer pumping, resembling changes in aged mice.Mice with one working copy of the protein’s gene had enlarged, scarred hearts and poorer pumping, resembling changes in aged mice.

Mouse studyMechanisms
Paper

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