American Journal of Physiology Cell Physiology·Sep 16Obesity-induced changes in ultrastructure and calcium release of female rat cardiomyocytes are partially reversed by aerobic exerciseExperiments in ratsAerobic exercisePaper
Nature Communications·Sep 11InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevityExperiments in wormsMitochondrial fission and fusionPaper
The Journal of Physiology·Aug 4Sedentary ageing remodels the structure-function relationships that underlie calcium signalling at super-resolution scales in the heartExperiments in rat cellsMechanismsPaper
Cell Reports·Jul 19TTYH3 regulates a lysosomal chloride conductance and controls lysosomal fusion, autophagy and senescenceExperiments in cellsAutophagyPaper
Current Neuropharmacology·Jun 9Rejuvenating Inter-organellar Communication Via Mitophagy in Ageing and NeurodegenerationReviewMitophagyPaper
International Journal of Molecular Sciences·Mar 28Unveiling Systemic Biomarkers and Metabolic Mechanisms in Glaucoma Progression from Multi-Omics InsightsMendelian randomization in peopleGlaucomaPaper
Advanced Science·Oct 3Enhanced Selenium Supplement Extends Lifespan and Delays Multi-Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium HomeostasisExperiments in miceInterventionsPaper
bioRxiv·Sep 15InsP3R signaling mediates mitochondrial stress-induced longevity through actomyosin-dependent mitochondrial dynamicsPreprint: experiments in wormsMitochondrial fission and fusionPaper
Autophagy·Sep 13Urolithin Α modulates inter-organellar communication via calcium-dependent mitophagy to promote healthy ageingExperiments in wormsInterventionsPaper
Free Radical Biology & Medicine·Sep 28Regulation of lysosomes in skeletal muscle during exercise, disuse and agingReviewLysosomePaper
bioRxiv·Mar 6Ultraviolet B acts as a dietary restriction mimetic by targeting mitochondrial bioenergeticsPreprint: experiments in wormsMitochondrionPaper
Journal of Cachexia, Sarcopenia and Muscle·Jan 15Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathyExperiments in human cellsCellular senescencePaper
FASEB Journal·Sep 12Zinc finger protein ZBTB17 controls cellular senescence via interacting with nuclear receptor RXRA and its downstream calcium signalingExperiments in human cellsOxidative stress and ROS signalingPaper
Molecular Neurodegeneration·Apr 21Carriers of the p.P522R variant in PLCγ2 have a slightly more responsive immune systemCohort study in peopleImmune responsePaper
JCSM Rapid Communications·Feb 18Ageing contributes to phenotype transition in a mouse model of periodic paralysisExperiments in miceMechanismsPaper
Journal of Cachexia, Sarcopenia and Muscle·Jan 11Numb is required for optimal contraction of skeletal muscleExperiments in miceMusclePaper
Calcified Tissue International·Oct 30BMP-2 Induced Signaling Pathways and Phenotypes: Comparisons Between Senescent and Non-senescent Bone Marrow Mesenchymal Stem CellsExperiments in human cellsp38 MAPK signalingPaper
International Journal of Molecular Sciences·Aug 28Ageing Causes Ultrastructural Modification to Calcium Release Units and Mitochondria in CardiomyocytesExperiments in miceMitochondrionPaper
International Journal of Molecular Sciences·Jul 3Improper Remodeling of Organelles Deputed to Ca²⁺ Handling and Aerobic ATP Production Underlies Muscle Dysfunction in AgeingReviewOxidative phosphorylationPaper
American Journal of Primatology·May 7Studies of aging nonhuman primates illuminate the etiology of early-stage Alzheimer's-like neuropathology: An evolutionary perspectiveReviewMechanismsPaper
Nature Communications·Feb 1Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and agingExperiments in miceCellular senescencePaper
The Journal of Clinical Investigation·Jan 5Complement C3a receptor-mediated vascular dysfunction: a complex interplay between aging and neurodegenerationReviewMechanismsPaper
Molecular Psychiatry·Dec 16The genie in the bottle-magnified calcium signaling in dorsolateral prefrontal cortexReviewMechanismsPaper
Cell Reports·Sep 10Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium HomeostasisExperiments in model organismsMechanismsPaper
Scientific Reports·Feb 6Improved Calcium Homeostasis and Force by Selenium Treatment and Training in Aged Mouse Skeletal MuscleExperiments in animalsInterventionsPaper
Cell Metabolism·Jun 18Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPKExperiments in animalsMechanismsPaper
Molecular Medicine Reports·May 22Resveratrol alleviates inflammatory injury and enhances the apoptosis of fibroblast‑like synoviocytes via mitochondrial dysfunction and ER stress in rats with adjuvant arthritisExperiments in ratsResveratrolPaper
Aging Cell·Sep 15The nuclear receptor RXRA controls cellular senescence by regulating calcium signalingExperiments in cellsOxidative stress and ROS signalingPaper
Experimental Gerontology·Aug 14Effect of acute muscle contusion injury, with and without dietary fish oil, on adult and aged male rats: contractile and biochemical responsesExperiments in animalsInterventionsPaper