Aging Cell
MTR4 protein restores youthful traits in human blood vessel cells
In laboratory experiments, depleting the protein triggered premature senescence, a state in which cells stop dividing, in human umbilical vein cells.In laboratory experiments, depleting the protein triggered premature senescence, a state in which cells stop dividing, in human umbilical vein cells.
Human cell studyMechanisms
Who was studiedSenescent human vascular endothelial cells, against vector-control senescent cells
What changedMarkers of cell aging fell in senescent human blood vessel cells overexpressing MTR4 compared with vector-control cells
The catchSenescence markers served as proxies for restored cellular youth