Blood DNA methylation
Biomarker1 paper1 finding
- Humans1
Associations
1Biological age
upin humans1
1 study
Biological age
upin humans1
Blood DNA methylation is associated with biological age in humans (ρ = +0.153, p = 0.005).
Humanscorrelation between discovery and replication dependency effect sizesblood
Blood methylation framework links aging hallmarks to organ patterns across humans · Preprints.org · 28 Sep 2026 · Preprint
Latest
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Corticosterone treatment shifts DNA methylation profiles in young chicks toward those of older birds and reshapes longevity pathways.
DNA methylation proxies of senescence markers track human disease and mortality
The new blood-based tools estimate senescence gene activity to predict incident diseases, all-cause mortality, and clinical treatment responses.
Blood methylation framework links aging hallmarks to organ patterns across humans
The computational approach identified reproducible conditional dependencies across two cohorts, highlighting stem cell maintenance and senescence regulation as broad markers of organ aging.
Blood methylation clocks capture two distinct biological domains of aging
Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle exposures.