Astrocyte signatures

1 paper1 finding

In silico1

Associations

1

Longer-lifespan-associated genetic variants

downin humans1

1 study

longer-lifespan-associated genetic variants are associated with astrocyte signatures in humans.
“astrocyte signatures were downregulated.”
Humanstranscriptome-wide association analysis of longer lifespan
Tissue-Resolved Transcriptome-Wide Association Study Reveals Targeted NAD⁺ Salvage, Synaptic Refinement, and Reduced Insulin Drive as Transcriptional Mechanisms of Human Lifespan
Figshare7 Apr 2026Preprint

Latest

2 in 12 months

Frontiers in Aging3 Sep

A minimal three-arm oral regimen for healthspan: mechanistic alignment with transcriptomic signals from a large parental-lifespan GWAS

CommentaryInterventions

Figshare7 Apr

Tissue-Resolved Transcriptome-Wide Association Study Reveals Targeted NAD⁺ Salvage, Synaptic Refinement, and Reduced Insulin Drive as Transcriptional Mechanisms of Human Lifespan

Preprint: computational studySynapse