A* gradient

1. A* gradient predicts wrinkle formation in humans.

   “the 10-year longitudinal study demonstrated that the a* gradient was associated with current and future skin ageing-related attributes, such as increased skin texture and wrinkle formation.”

   Humansskin10 yearsfemales

   Skin inflammatory signatures, as measured by disordered spatial redness patterns, predict current and future skin ageing attributes

   Experimental dermatology·Aug 1, 2024

1. A* gradient is associated with cellular senescence in humans.

   “Transcriptome analysis revealed upregulation of genes related to acute inflammation, chronic inflammation, cellular senescence, and angiogenesis in subjects with higher a* gradients.”

   Humansskinfemales

   Skin inflammatory signatures, as measured by disordered spatial redness patterns, predict current and future skin ageing attributes

   Experimental dermatology·Aug 1, 2024

More on Cellular senescence

1. A* gradient is associated with IL-8 in humans.

   “A significant correlation was observed between the a* gradient and the levels of inflammatory cytokines (IL-1Ra/IL-1α and IL-8).”

   Humansskinfemales

   Skin inflammatory signatures, as measured by disordered spatial redness patterns, predict current and future skin ageing attributes

   Experimental dermatology·Aug 1, 2024

More on IL-8