Brain agingHumans175 adultsCross-sectional study

Arterial Stiffness and Anti-NR2/GluN2 Autoantibodies to N-Methyl-D-Aspartate Receptors as Markers of Vascular Aging and Cognitive Impairment in Arterial Hypertension

Figure 1. Area under the curve of the developed multivariable logistic regression model.
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Figure 1. Area under the curve of the developed multivariable logistic regression model.Area under the curve of the developed multivariable logistic regression model.Safronova et al. · CC BY

Life

Abstract

Background Arterial hypertension (HTN) is associated with accelerated vascular aging, cerebral microvascular injury, and cognitive decline. Anti-NR2/GluN2 (NR2) antibodies may be related to N-methyl-D-aspartate receptor (NMDAR)-mediated neuronal-ischemic injury, although their clinical significance in HTN requires further clarification.

The paper

Sechenov University

Life · 26 Aug 2026 · CC BY

doi.org/10.3390/life16091418PubMed 42795283

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