primate
3 papers6 findings
- Animals2
Interventions
3Ascorbic acid
downbiological age of oocytes1downbiological age of somatic cells1downfollicular depletion1
1 study
Ascorbic acid
downbiological age of oocytes1downbiological age of somatic cells1downfollicular depletion1
Ascorbic acid decreases follicular depletion in primate.
“Vitamin C diminishes key aging biomarkers, including oxidative stress and follicular depletion.”
Animalsoralovary3.3-year
Vitamin C conveys geroprotection on primate ovaries
Cell stem cell14 Oct 2025
Ascorbic acid decreases biological age of somatic cells in primate (-5.66 years).
“somatic cells by 5.66 years”
Animalsoralovary3.3-year
Vitamin C conveys geroprotection on primate ovaries
Cell stem cell14 Oct 2025
Ascorbic acid decreases biological age of oocytes in primate (-1.35 years).
“vitamin C can reduce the biological age of oocytes by 1.35 years”
Animalsoralovary3.3-year
Vitamin C conveys geroprotection on primate ovaries
Cell stem cell14 Oct 2025
GRHL2 gene therapy
downprostate aging1downurinary dysfunction1
1 study
GRHL2 gene therapy
downprostate aging1downurinary dysfunction1
GRHL2 gene therapy decreases urinary dysfunction in primate.
“alleviated age-related urinary dysfunction in vivo”
Animalsprostate
Reprogramming the GRHL2-CDK19 axis by gene therapy alleviates prostate aging
Nature aging20 Nov 2025
GRHL2 gene therapy decreases prostate aging in primate.
“a single injection of a GRHL2-based gene therapy strategy delayed prostate aging”
Animalsprostate
Reprogramming the GRHL2-CDK19 axis by gene therapy alleviates prostate aging
Nature aging20 Nov 2025
GDF7 neutralization
upvisual function1
1 study
GDF7 neutralization
upvisual function1
GDF7 neutralization improves visual function in primate.
“proof-of-concept studies of GDF7 neutralization in primate models and the OSK-factor reprogramming in aged and glaucoma mice models, show that epigenetic changes are reversible and can restore visual functions.”
Reviewin primate models
Emerging role of epigenetic mechanisms in glaucoma and their translational potential
Frontiers in genetics23 Feb 2026