primate

Organism

3 papers6 findings

  • Animals2

Interventions

3

Ascorbic acid

downbiological age of oocytes1downbiological age of somatic cells1downfollicular depletion1

1 study
  1. Ascorbic acid decreases follicular depletion in primate.

    “Vitamin C diminishes key aging biomarkers, including oxidative stress and follicular depletion.”

    Animalsoralovary3.3-year

    Vitamin C conveys geroprotection on primate ovaries

    Cell stem cell14 Oct 2025

  2. Ascorbic acid decreases biological age of somatic cells in primate (-5.66 years).

    “somatic cells by 5.66 years”

    Animalsoralovary3.3-year

    Vitamin C conveys geroprotection on primate ovaries

    Cell stem cell14 Oct 2025

  3. Ascorbic acid decreases biological age of oocytes in primate (-1.35 years).

    “vitamin C can reduce the biological age of oocytes by 1.35 years”

    Animalsoralovary3.3-year

    Vitamin C conveys geroprotection on primate ovaries

    Cell stem cell14 Oct 2025

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GRHL2 gene therapy

downprostate aging1downurinary dysfunction1

1 study
  1. GRHL2 gene therapy decreases urinary dysfunction in primate.

    “alleviated age-related urinary dysfunction in vivo”

    Animalsprostate

    Reprogramming the GRHL2-CDK19 axis by gene therapy alleviates prostate aging

    Nature aging20 Nov 2025

  2. GRHL2 gene therapy decreases prostate aging in primate.

    “a single injection of a GRHL2-based gene therapy strategy delayed prostate aging”

    Animalsprostate

    Reprogramming the GRHL2-CDK19 axis by gene therapy alleviates prostate aging

    Nature aging20 Nov 2025

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GDF7 neutralization

upvisual function1

1 study
  1. GDF7 neutralization improves visual function in primate.

    “proof-of-concept studies of GDF7 neutralization in primate models and the OSK-factor reprogramming in aged and glaucoma mice models, show that epigenetic changes are reversible and can restore visual functions.”

    Reviewin primate models

    Emerging role of epigenetic mechanisms in glaucoma and their translational potential

    Frontiers in genetics23 Feb 2026

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