Weight loss
Intervention1 paper4 findings
Outcomes
3Estradiol
downin humans1no changein humans1Moderate certainty
1 study
Estradiol
downin humans1no changein humans1Moderate certainty
Weight loss decreases estradiol in humans.
Reviewpostmenopausal women
Adiposity and sex steroid hormones: evidence on direct measures and changes over time -- a systematic review and meta-analysis · medRxiv · 26 Sep 2026 · Preprint
Weight loss has no effect on estradiol in humans.
Reviewpremenopausal
Adiposity and sex steroid hormones: evidence on direct measures and changes over time -- a systematic review and meta-analysis · medRxiv · 26 Sep 2026 · Preprint
SHBG
upin humans1Moderate certainty
1 study
SHBG
upin humans1Moderate certainty
Weight loss increases SHBG in humans.
Reviewweight loss intervention
Adiposity and sex steroid hormones: evidence on direct measures and changes over time -- a systematic review and meta-analysis · medRxiv · 26 Sep 2026 · Preprint
Testosterone
downin humans1Moderate certainty
1 study
Testosterone
downin humans1Moderate certainty
Weight loss decreases testosterone in humans.
Reviewweight loss intervention
Adiposity and sex steroid hormones: evidence on direct measures and changes over time -- a systematic review and meta-analysis · medRxiv · 26 Sep 2026 · Preprint