Very low energy ketogenic therapy

Intervention

3 papers5 findings

  • 1 lab in 1 country
  • Human trial2

Outcomes

5

Systolic blood pressure

no changein humans1

1 study
  1. Very low energy ketogenic therapy has no effect on systolic blood pressure in humans.

    “systolic blood pressure did not show a significant change”

    Human trial45 days

    MON-638 Impact of Very Low Energy Ketogenic Therapy on Metabolic Syndrome: Effects on Weight, Cardiometabolic Health, and Sustainability

    ENDO 2025 abstract22 Oct 2025

Triglyceride

downin humans1

1 study
  1. Very low energy ketogenic therapy decreases triglyceride in humans.

    “triglyceride (TG) levels showed a marked reduction in the MetS group”

    Human trialin metabolic syndrome patients45 days

    MON-638 Impact of Very Low Energy Ketogenic Therapy on Metabolic Syndrome: Effects on Weight, Cardiometabolic Health, and Sustainability

    ENDO 2025 abstract22 Oct 2025

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Diastolic blood pressure

downin humans1

1 study
  1. Very low energy ketogenic therapy decreases diastolic blood pressure in humans (70.0 mmHg vs. 80.0 mmHg, p = 0.016).

    “A notable improvement in diastolic blood pressure was observed (70.0 mmHg vs. 80.0 mmHg, p = 0.016)”

    Human trialin metabolic syndrome patients45 days

    MON-638 Impact of Very Low Energy Ketogenic Therapy on Metabolic Syndrome: Effects on Weight, Cardiometabolic Health, and Sustainability

    ENDO 2025 abstract22 Oct 2025

Body weight

downin humans1

1 study
  1. Very low energy ketogenic therapy decreases body weight in humans (88.4 ± 11.1 kg vs. 97.6 ± 12.1 kg, p = 0.011).

    “Body weight (BW) significantly decreased from baseline to the end of the VLEKT phase (88.4 ± 11.1 kg vs. 97.6 ± 12.1 kg, p = 0.011)”

    Human trialin metabolic syndrome patients45 days

    MON-638 Impact of Very Low Energy Ketogenic Therapy on Metabolic Syndrome: Effects on Weight, Cardiometabolic Health, and Sustainability

    ENDO 2025 abstract22 Oct 2025

Obesity

downin humans1

1 study
  1. Very low energy ketogenic therapy decreases obesity in humans.

    “VLEKT is an innovative approach to obesity treatment, offering a target-oriented and highly effective strategy for people fighting against overweight and its associated medical complications.”

    Review

    Advancing Obesity Management: the Very Low-Energy Ketogenic therapy (VLEKT) as an Evolution of the "Traditional" Ketogenic Diet

    Current obesity reports3 Apr 2025

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