VCAM-1-POSITIVE umbilical cord mesenchymal stem cell-derived exosomes

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: National Natural Science Foundation of China

Animals1

Outcomes

Cardiac function

upin rats1

1 study

VCAM-1-POSITIVE umbilical cord mesenchymal stem cell-derived exosomes improve cardiac function in rats.
“VCAM-1+ MSCs or exosome administration significantly alleviated these effects, and improved cardiac function.”
Animalsdiabetic cardiomyopathyheart
Reparative effects of VCAM-1 high-performance MSC-derived exosomes on aged diabetic cardiomyocyte injury: a focus on ferroptosis suppression
Apoptosis : an international journal on programmed cell death10 Jan 2026

Ferroptosis

downin rat cells1

1 study

VCAM-1-POSITIVE umbilical cord mesenchymal stem cell-derived exosomes decrease ferroptosis in rat cells.
“VCAM-1+-UC-MSCs-derived exosomes attenuate cardiomyocyte ferroptosis by suppressing Ras/Raf/MEK/ERK/c-FOS pathway”
Cellshigh-glucose-damaged senescent cardiomyocytescardiomyocyte
Reparative effects of VCAM-1 high-performance MSC-derived exosomes on aged diabetic cardiomyocyte injury: a focus on ferroptosis suppression
Apoptosis : an international journal on programmed cell death10 Jan 2026

Latest

1 in 12 months

Apoptosis10 Jan

Reparative effects of VCAM-1 high-performance MSC-derived exosomes on aged diabetic cardiomyocyte injury: a focus on ferroptosis suppression

Experiments in ratsInterventions

Paper

VCAM-1-POSITIVE umbilical cord mesenchymal stem cell-derived exosomes

Outcomes

Latest

Reparative effects of VCAM-1 high-performance MSC-derived exosomes on aged diabetic cardiomyocyte injury: a focus on ferroptosis suppression

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