UBCS039
- 1 lab in 1 country
- Funders: Education Department of Shaanxi Province and 1 more
- Animals1
Outcomes
1Cellular senescence
downin cells1
1 study
Cellular senescence
downin cells1
UBCS039 decreases cellular senescence in cells.
“SIRT6 activation (UBCS039) suppressed LINE1-cGAS-STING signaling and alleviated senescence”
Cellsin hypoxic PASMCs
Cellular signalling3 Jan 2026
Latest
1 in 12 monthsCellular Signalling
Nuclear SIRT6 depletion activates LINE1-cGAS-STING pathway to induce PASMCs senescence in hypoxic pulmonary hypertension
Experiments in animalscGAS–STING signalling