UBCS039

  • 1 lab in 1 country
  • Funders: Education Department of Shaanxi Province and 1 more
  • Animals1

Outcomes

1

Cellular senescence

downin cells1

1 study
  1. UBCS039 decreases cellular senescence in cells.

    “SIRT6 activation (UBCS039) suppressed LINE1-cGAS-STING signaling and alleviated senescence”

    Cellsin hypoxic PASMCs

    Nuclear SIRT6 depletion activates LINE1-cGAS-STING pathway to induce PASMCs senescence in hypoxic pulmonary hypertension

    Cellular signalling3 Jan 2026

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