Tris(1-chloro-2-propyl) phosphate
1 paper studies it3 findings
- 1 lab in 1 country
- Funders: National Forestry and Grassland Administration and 1 more
- Cells1
Outcomes
3Cell cycle regulation
downin human cells1
1 study
Cell cycle regulation
downin human cells1
Tris(1-chloro-2-propyl) phosphate inhibits cell cycle regulation in human cells.
“the cell cycle was arrested at the G1 phase at 100 μg/mL”
Cells100 μg/mL24 h
International journal of molecular sciencesNov 18, 2022
DNA damage response
upin human cells1
1 study
DNA damage response
upin human cells1
Tris(1-chloro-2-propyl) phosphate induces DNA damage response in human cells.
“triggered DNA damage, evidenced by an increase of phosphorylated histone H2A.X (γH2A.X) in the nucleus”
Cells24 h
International journal of molecular sciencesNov 18, 2022
Cell viability
downin human cells1
1 study
Cell viability
downin human cells1
Tris(1-chloro-2-propyl) phosphate decreases cell viability in human cells (IC50 of 275 μg/mL).
“TCPP caused a concentration-dependent decrease in HaCaT cell viability after exposure to 1.56-400 μg/mL for 24 h, with an IC50 of 275 μg/mL”
Cells24 h
International journal of molecular sciencesNov 18, 2022
Latest
International Journal of Molecular Sciences
Organophosphorus Flame Retardant TCPP Induces Cellular Senescence in Normal Human Skin Keratinocytes: Implication for Skin Aging
Experiments in human cellsCellular senescence