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Transition metal dichalcogenide nanoflowers

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: National Institute of General Medical Sciences
  • Model organisms1

Outcomes

2

Aggregated alpha-synuclein

downin worms1

1 study

  1. Transition metal dichalcogenide nanoflowers decrease aggregated alpha-synuclein in worms.

    “Nematodes that received NFs experienced a drastic reduction in the amount of aggregated α-syn”

    Model organismsin Caenorhabditis elegans that overexpress α-syn

    Neuroprotective Parkinson's Disease Therapeutic: Transition Metal Dichalcogenide Nanoflower Treatments Alleviate Pathological Cell Stress

    bioRxiv : the preprint server for biology1 Oct 2025Preprint

More on Aggregated alpha-synuclein

Lifespan

upin worms1

1 study

  1. Transition metal dichalcogenide nanoflowers extend lifespan in worms.

    “resulted in a significant increase in C. elegans lifespan”

    Model organismsin Caenorhabditis elegans that overexpress α-syn

    Neuroprotective Parkinson's Disease Therapeutic: Transition Metal Dichalcogenide Nanoflower Treatments Alleviate Pathological Cell Stress

    bioRxiv : the preprint server for biology1 Oct 2025Preprint

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