Tpra nanoparticles

1. Tpra nanoparticles decrease lipid peroxidation in worms.

   “TPRA NPs markedly attenuated ferroptosis-associated markers by decreasing excess iron, lipid peroxidation, and ROS”

   Model organismsin worms induced with MPP+, erastin, or iron

   Reactive Oxygen Species-Responsive Targeted Polydopamine-Rosmarinic Acid Nanotherapeutics for Ferroptosis-Driven Parkinson's Disease Modulation in Caenorhabditis elegans

   ACS applied bio materials·20 May 2026

More on Lipid peroxidation

1. Tpra nanoparticles improve neurobehavioral function in worms.

   “preserved the viability of DA neurons and restored neurobehavioral function and mitochondrial integrity”

   Model organismsin worms induced with MPP+, erastin, or iron

   Reactive Oxygen Species-Responsive Targeted Polydopamine-Rosmarinic Acid Nanotherapeutics for Ferroptosis-Driven Parkinson's Disease Modulation in Caenorhabditis elegans

   ACS applied bio materials·20 May 2026

More on Neurobehavioral function

1. Tpra nanoparticles decrease α-synuclein deposition in worms.

   “TPRA NPs reduced α-synuclein deposition, lengthened lifespan, and activated SKN-1 signaling”

   Model organismsin α-Syn expressing NL5901 worms

   Reactive Oxygen Species-Responsive Targeted Polydopamine-Rosmarinic Acid Nanotherapeutics for Ferroptosis-Driven Parkinson's Disease Modulation in Caenorhabditis elegans

   ACS applied bio materials·20 May 2026

More on α-synuclein deposition

1. Tpra nanoparticles extend lifespan in worms.

   “TPRA NPs reduced α-synuclein deposition, lengthened lifespan, and activated SKN-1 signaling”

   Model organismsin α-Syn expressing NL5901 worms

   Reactive Oxygen Species-Responsive Targeted Polydopamine-Rosmarinic Acid Nanotherapeutics for Ferroptosis-Driven Parkinson's Disease Modulation in Caenorhabditis elegans

   ACS applied bio materials·20 May 2026