Thymol

Intervention

1 paper4 findings

PubChemChEBI

  • 1 lab in 1 country
  • Funders: Chongqing Medical University and 1 more
  • Animals1

Outcomes

4

Sex hormone signalling (oestrogen, androgen)

upin mice1

1 study
  1. Thymol increases sex hormone signalling (oestrogen, androgen) in mice (1.6-1.8-fold).

    “elevated serum estradiol and progesterone levels to 1.6-1.8-fold of aged controls”

    Animalsin aged pregnant micefemalesn = 4

    Thymol Mitigates Oxidative Stress-Induced Ovarian Aging and Restores Steroidogenesis via the JAK1-STAT3 Pathway

    Current issues in molecular biology2 Nov 2025

More on Sex hormone signalling (oestrogen, androgen)

Viable fetus numbers

upin mice1+40%

1 study
  1. Thymol increases viable fetus numbers in mice (about 40%).

    “In aged pregnant mice (n = 4 per group), thymol increased viable fetus numbers by about 40%”

    Animalsin aged pregnant micefemalesn = 4

    Thymol Mitigates Oxidative Stress-Induced Ovarian Aging and Restores Steroidogenesis via the JAK1-STAT3 Pathway

    Current issues in molecular biology2 Nov 2025

JAK–STAT signalling

downin human cells1

1 study
  1. Thymol inhibits JAK–STAT signalling in human cells.

    “inhibited JAK1-STAT3 phosphorylation (n = 3, p < 0.05)”

    Cellsin t-BHP-treated human granulosa-like tumor cellsgranulosa cell40 μg/mLn = 3

    Thymol Mitigates Oxidative Stress-Induced Ovarian Aging and Restores Steroidogenesis via the JAK1-STAT3 Pathway

    Current issues in molecular biology2 Nov 2025

More on JAK–STAT signalling

Reactive oxygen species

downin human cells1−35%

1 study
  1. Thymol decreases reactive oxygen species in human cells (about 35%).

    “reduced reactive oxygen species accumulation by about 35% (p < 0.05)”

    Cellsin t-BHP-treated human granulosa-like tumor cellsgranulosa cell40 μg/mLn = 3

    Thymol Mitigates Oxidative Stress-Induced Ovarian Aging and Restores Steroidogenesis via the JAK1-STAT3 Pathway

    Current issues in molecular biology2 Nov 2025

More on Reactive oxygen species

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