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Sympathetic depletion

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Key Research and Development Program of Liaoning Province and 4 more
  • Animals1

Outcomes

1

Osteoarthritis

downin mice1

1 study

  1. Sympathetic depletion protects against osteoarthritis in mice.

    “sympathetic depletion through TH was shown to ameliorate OA progression in aging mice”

    Animalsthrough TH depletion in aging micejoint

    Sympathetic innervation induces exosomal miR-125 transfer from osteoarthritic chondrocytes, disrupting subchondral bone homeostasis and aggravating cartilage damage in aging mice

    Journal of advanced research28 Mar 2024

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