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BETA-1 adrenergic receptor blocker

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Key Research and Development Program of Liaoning Province and 4 more
  • Animals1

Outcomes

1

Osteoarthritis

downin mice1

1 study

  1. BETA-1 adrenergic receptor blocker protects against osteoarthritis in mice.

    “knockout of β1-adrenergic receptor or treatment with a β1-adrenergic receptor blocker attenuated OA progression in aging mice”

    Animalsin aging micejoint

    Sympathetic innervation induces exosomal miR-125 transfer from osteoarthritic chondrocytes, disrupting subchondral bone homeostasis and aggravating cartilage damage in aging mice

    Journal of advanced research28 Mar 2024

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