Surgical menopause

Exposure

4 papers3 findings

  • 2 independent labs in 2 countries
  • Humans3

Associations

3

Endocan

upin humans1

1 study
  1. Surgical menopause is associated with endocan in humans.

    “Serum endocan concentrations differed significantly among the three groups (overall p < 0.001), with the highest levels in surgical menopause, followed by natural menopause and premenopause.”

    Humansadjusted for age and BMIfemales

    Comparison of Carotid Intima-Media Thickness and Serum Endocan Levels in Surgical and Natural Menopause With Premenopausal Women

    The journal of obstetrics and gynaecology research1 Sep 2026

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Alzheimer's disease and related dementias

upin humans1

1 study
  1. Surgical menopause raises the risk of Alzheimer's disease and related dementias in humans.

    “Surgical menopause was linked with 1.22 [1.12,1.33] higher hazard of ADRD controlling for hormones, and 1.15 [1.04,1.25] higher hazard with full adjustment.”

    Humansfemales

    The Role of Reproductive Aging and Surgeries for Alzheimer's Disease and Related Dementias (ADRD) Diagnoses in the Cardiovascular Health Study

    AAIC 2025 abstract23 Dec 2025

More on Alzheimer's disease and related dementias

Metabolic syndrome

upin humans1

1 study
  1. Surgical menopause raises the risk of metabolic syndrome in humans.

    “surgical menopause is strongly linked with a higher incidence of MetS.”

    Reviewfemales

    Metabolic Syndrome During Menopause

    Current vascular pharmacology1 Jan 2019

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