Androgens
Biomarker2 papers
- Humans1
Funding
National Heart, Lung, and Blood InstituteUS$1.9m2 grants since 2023
Latest
365-ARI use is tied to lower laryngeal cancer risk in men
In a Swedish cohort, 5-ARI users had a 17% lower risk of laryngeal or hypopharyngeal squamous cell carcinoma than nonusers (adjusted hazard ratio…In a Swedish cohort, 5-ARI users had a 17% lower risk of laryngeal or hypopharyngeal squamous cell carcinoma than nonusers (adjusted hazard ratio, 0.83).
Androgen receptor polyglutamine tract controls muscle growth and atrophy pathways
Researchers found that expanding polyglutamine tracts in the androgen receptor shift binding toward senescence-linked enhancers, driving muscle…Researchers found that expanding polyglutamine tracts in the androgen receptor shift binding toward senescence-linked enhancers, driving muscle atrophy in cells and mice.
Human vellus hair units undergo cellular and metabolic remodeling during skin aging
A single-nucleus atlas reveals stem cell loss, altered sebocyte activity, and shifted immune interactions in the hair follicles of older men.A single-nucleus atlas reveals stem cell loss, altered sebocyte activity, and shifted immune interactions in the hair follicles of older men.
Oestradiol levels do not predict heart events in older women
In 5,535 women aged 70 and older, endogenous oestradiol concentrations showed no association with major cardiovascular events or all-cause mortality…In 5,535 women aged 70 and older, endogenous oestradiol concentrations showed no association with major cardiovascular events or all-cause mortality over 4.5 years of follow-up.