Strenuous exercise
2 papers4 findings
- 1 lab in 1 country
- Humans1
Outcomes
4Cardiorespiratory fitness
downin humans1
1 study
Cardiorespiratory fitness
downin humans1
Strenuous exercise decreases cardiorespiratory fitness in humans (g = -0.23, 95% CI -0.44 to -0.01).
“reduced VO2max (g = - 0.23, 95% CI - 0.44 to - 0.01, p = 0.038)”
Reviewexhaustive and/or strenuous exercise
Biogerontology25 Feb 2026
IL-6
upin humans1
1 study
IL-6
upin humans1
Strenuous exercise increases IL-6 in humans (g = 0.97, 95% CI 0.04 to 1.91).
“upregulated IL-6 (g = 0.97, 95% CI 0.04 to 1.91, p = 0.042)”
Reviewexhaustive and/or strenuous exercise
Biogerontology25 Feb 2026
8-hydroxy-2'-deoxyguanosine
upin humans1
1 study
8-hydroxy-2'-deoxyguanosine
upin humans1
Strenuous exercise increases 8-hydroxy-2'-deoxyguanosine in humans (g = 0.97, 95% CI 0.03 to 0.80).
“increased 8-OHdG levels (g = 0.97, 95% CI 0.03 to 0.80, p = 0.036)”
Reviewexhaustive and/or strenuous exercise
Biogerontology25 Feb 2026
Telomere length
downin humans1
1 study
Telomere length
downin humans1
Strenuous exercise decreases telomere length in humans (g = -0.44, 95% CI -0.83 to -0.03).
“Exhaustive and/or strenuous exercise significantly shortened telomere length (g = - 0.44, 95% CI - 0.83 to - 0.03, p = 0.037)”
Reviewexhaustive and/or strenuous exercise
Biogerontology25 Feb 2026