Scutellarein

1. Scutellarein decreases inflammation in rat cells.

   “partially inhibited the nuclear factor kappa-B/mitogen-activated protein kinase (NF-κB/MAPK) pathway, thereby reducing inflammatory cytokine production in the joint cartilage”

   Cellsunder IL-1β interventionjoint cartilage

   Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats

   Current medical science·Apr 4, 2024

More on Inflammation

1. Scutellarein decreases cartilage damage in rats.

   “SCU (at a dose of 50 mg/kg) administered for 2 months could significantly delay the progression of cartilage damage”

   Animalscartilage50 mg/kg2 months

   Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats

   Current medical science·Apr 4, 2024

1. Scutellarein decreases apoptosis in rat cells.

   “Furthermore, SCU significantly reduced IL-1β-induced apoptosis and senescence in rat chondrocytes”

   Cellsunder IL-1β interventionchondrocytes

   Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats

   Current medical science·Apr 4, 2024

More on Apoptosis

1. Scutellarein decreases cellular senescence in rat cells.

   “Furthermore, SCU significantly reduced IL-1β-induced apoptosis and senescence in rat chondrocytes”

   Cellsunder IL-1β interventionchondrocytes

   Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats

   Current medical science·Apr 4, 2024

More on Cellular senescence