Scorpion venom heat-resistant synthesized peptide

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funder: Dalian Medical University
  • Animals1

Outcomes

4

Cellular senescence

downin mice1

1 study
  1. Scorpion venom heat-resistant synthesized peptide decreases cellular senescence in mice.

    “SVHRSP demonstrated a decline in senescent markers, including SA-β-gal enzyme activity, p16, p12, Sirt1 and cell cycle arrest”

    Animalsagingbrain

    SVHRSP alleviates age-related cognitive deficiency by reducing oxidative stress and neuroinflammation through Sirt 1 pathway

    Research Square5 Mar 2024Preprint

More on Cellular senescence

Oxidative stress and ROS signalling

downin mice1

1 study
  1. Scorpion venom heat-resistant synthesized peptide decreases oxidative stress and ROS signalling in mice.

    “reduction in oxidative stress-induced damage”

    Animalsagingbrain

    SVHRSP alleviates age-related cognitive deficiency by reducing oxidative stress and neuroinflammation through Sirt 1 pathway

    Research Square5 Mar 2024Preprint

More on Oxidative stress and ROS signalling

Inflammation

downin mice1

1 study
  1. Scorpion venom heat-resistant synthesized peptide decreases inflammation in mice.

    “SVHRSP attenuated neuroinflammation by regulating the NF-κB nucleoplasmic distribution”

    Animalsagingbrain

    SVHRSP alleviates age-related cognitive deficiency by reducing oxidative stress and neuroinflammation through Sirt 1 pathway

    Research Square5 Mar 2024Preprint

More on Inflammation

Cognitive function

upin mice1

1 study
  1. Scorpion venom heat-resistant synthesized peptide improves cognitive function in mice.

    “SVHRSP significantly ameliorated age-related cognitive decline”

    Animalsagingbrain

    SVHRSP alleviates age-related cognitive deficiency by reducing oxidative stress and neuroinflammation through Sirt 1 pathway

    Research Square5 Mar 2024Preprint

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