SB-431542

Intervention1 paper1 findingPubChem 4521392ChEBI 91108

Humans1

Outcomes

1

Activin a

downin human cells1

1 study

SB-431542 inhibits activin a in human cells.
“and these effects were attenuated by SB431542, a small-molecule inhibitor of ALK4/5/7 signalling.”
Cellsattenuating Activin A suppression of myogenic regulators in primary human MuSCssatellite cell
Activin A from inflammatory macrophages impairs stem cell regulation in aging human muscle · International journal of molecular sciences · 17 Sep 2026

Latest

1

HumansInflammaging28 Sep

Activin A from inflammatory macrophages impairs stem cell regulation in aging human muscle

Researchers mapped signaling pathways between senescent-like immune cells and muscle stem cells across multiple human transcriptomic datasets.

International Journal of Molecular Sciences · Liu X et al.