Activin a
Intervention1 paper2 findingsMeSH C422405
- Humans1
Outcomes
1Myogenic regulators
downin human cells1
1 study
Myogenic regulators
downin human cells1
Activin a decreases myogenic regulators in human cells.
“In primary human MuSCs, Activin A induced Activin-responsive genes and suppressed myogenic regulators”
Cellsin primary human MuSCssatellite cell
Activin A from inflammatory macrophages impairs stem cell regulation in aging human muscle · International journal of molecular sciences · 17 Sep 2026
Upstream
1SB-431542
downin human cells1
1 study
SB-431542
downin human cells1
SB-431542 inhibits activin a in human cells.
“and these effects were attenuated by SB431542, a small-molecule inhibitor of ALK4/5/7 signalling.”
Cellsattenuating Activin A suppression of myogenic regulators in primary human MuSCssatellite cell
Activin A from inflammatory macrophages impairs stem cell regulation in aging human muscle · International journal of molecular sciences · 17 Sep 2026
Latest
1Activin A from inflammatory macrophages impairs stem cell regulation in aging human muscle
Researchers mapped signaling pathways between senescent-like immune cells and muscle stem cells across multiple human transcriptomic datasets.
International journal of molecular sciences · Liu X et al.