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Running exercise

Intervention

2 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals2

Outcomes

2

Histone lactylation

upin mice2

2 studies

  1. Running exercise increases histone lactylation in mice.

    “Running exercise increases histone lactylation”

    Animalsskeletal muscle

    Histone Lactylation Antagonizes Senescence and Skeletal Muscle Aging by Modulating Aging-Related Pathways

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)19 May 2025

  2. Running exercise increases histone lactylation in mice.

    “running exercise enhances the level of histone lactylation and reconstructs the cell landscape and communications of mouse skeletal muscle”

    Animalsskeletal muscle

    Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming

    bioRxiv (Cold Spring Harbor Laboratory)26 May 2023Preprint

More on Histone lactylation

Skeletal muscle function

upin mice1

1 study

  1. Running exercise improves skeletal muscle function in mice.

    “running exercise enhances the level of histone lactylation and reconstructs the cell landscape and communications of mouse skeletal muscle, leading to rejuvenation and functional improvement.”

    Animalsskeletal muscle

    Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming

    bioRxiv (Cold Spring Harbor Laboratory)26 May 2023Preprint

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